Aromatherapy and appetite suppression: molecular mechanism by system biology

Document Type : Original Article

Authors

Department of Plant Biology, School of Biology, College of Science, University of Tehran, Tehran, Iran

Abstract

Obesity is a complex disease that results from chronic metabolic disorders and has become a significant global health concern. It is a medical issue and a significant risk factor for serious conditions such as insulin resistance, type 2 diabetes, cardiovascular disease, and certain types of cancer. Additionally, the psychological impact of obesity should not be overlooked, as it can lead to severe pathologies such as depression, phobias, generalized anxiety, and low self-esteem. While many conventional methods have been used to address this disorder, their severe side effects limit their efficacy and tolerability among the general population. In recent years, there has been a growing interest in aromatherapy as a safe method for preventing obesity. Essential oils (EOs) have demonstrated efficacy in promoting weight loss. EOs are mixtures of aromatic substances produced by various plants, especially those possessing medicinal and aromatic properties. In this study, we investigated the molecular mechanisms of bergamot, orange, lemon, peppermint, and ginger in treating obesity using a systems biology approach.

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